Hero Projects

Funded proposals

In the inaugural year of the Kren Engineering-based Medicine Initiative (KEMi), our primary objective was to fund research projects mainly focused on ophthalmology. This aligns with our mission to enhance the integration of engineering and technology in the fields of medicine and healthcare.

Despite the short two-week submission period, we received an overwhelming response to our call for proposals (CFPs). A total of 83 proposals were submitted, with 70 of them being engineering-based medicine projects. In response to the enthusiasm expressed by our faculty, our donor increased this year's support to fund additional engineering-based projects and a special Kren-Endowed chair. The selected proposals are listed below.

Engineering-based medicine projects

Towards Ubiquitous Hospital-Level Personalized Healthcare: Doctor Robot (DocBot): Healthcare Engineering with AI & Robotic Technology (HEART)

Principal investigator: Xu Chen, PhD, UW Mechanical Engineering

Co-principal investigator: Tueng T. Shen, MD, PhD, Professor, Ophthalmology and Bioengineering, SOM & COE

Integrating Engineering and Rehabilitation Medicine to Improve Healthcare and Assistive Technology Access and Customizability

Principal investigator: Jennifer Mankoff, PhD

Co-principal investigator: Heather A Feldner, PT, PhD, PCS, Associate Professor, Rehabilitation Medicine, SOM

Additional collaborator: Brennen Johnston, Washington Assistive Technology Act Program (WATAP) Assistive Technology Support Technician

Real Time Machine Vision to Enhance Emergency Intubation

Principal investigator: Nathan White, MD, MS

Co-principal investigators:

  • Jenq-Neng Hwang, PhD, Professor, Electrical Engineering, COE
  • Richard Utarnatchitt, MD, MS, Associate Professor, Emergency Medicine, SOM

Millimeter-Scale, Bioresorabable Uterine Sensors for Real-Time, Ultrasensitive Cytokine Monitoring During High-Risk Pregnancies

Principal investigator: Quansan Yang, PhD

Co-principal investigator: Steven A. McCartney, MD, PhD, Assistant Professor, Department of Obstetrics and Gynecology, SOM

Vision-based projects

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Advancing Volumetric Phase-Sensitive OCT for Wide-Field Functional Imaging of Trabecular Meshwork Dynamics

Principal investigator: Ruikang Wang, PhD, Professor, Bioengineering, COE

Leveraging the ADDF and EyeACT Datasets to Learn and Predict Dementia Thereby Identifying Dementia Biomarkers

Principal investigator: Yue Wu, PhD

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Early Detection of Photoreceptor Dysfunction in Outer Retinal Disease Using Optoretinography

Principal investigator: Ramkumar Sabesan, PhD

Co-principal investigators:

  • Jennifer Chao, MD, PhD, Professor, Ophthalmology
  • Debarshi Mustafi, MD, PhD, Assistant Professor, UW Ophthalmology and Seattle Children's Hospital

Wearable Assist Device to Improve Visual Function Following Restorative Therapy

Principal investigator: James A. Kuchenbecker, PhD

Co-principal investigators:

  • Russell Van Gelder, MD, PhD, Boyd K Bucey Memorial Professor and Chair, Ophthalmology
  • Ruikang Wang, PhD, Professor and George and Martina Kren Endowed Chair, Bioengineering

Injectable Biomaterial-Mediated Transplantation of Limbal Fibroblasts for Treatment of Limbal Stem Cell Deficiency

Principal investigator: Yuzuru Sasamoto, MD, PhD

Co-principal investigator: Cole DeForest, PhD, Associate Professor, Bioengineering, COE

Kren-Endowed chair project

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High-Resolution Facial Imaging for Non-Invasive Detection of Rhythm Irregularities and Perfusion Deficits in Atrial Fibrillation Patients

Principal investigator: Nazem Akoum, MD, MS, FACC, FAHA, FHRS

Co-principal investigator: Ruikang Wang, PhD, Professor, Bioengineering, COE